Steps to Manage Your Health

Some simple lifestyle changes can help you live with Alpha-1.

4 steps in the right direction7

1. Maintain a healthy diet and get plenty of exercise.

2. Stop smoking. Use alcohol with caution.

  • Quit smoking and stay away from secondhand smoke.
  • Drink alcohol sparingly, if at all. Alcoholic beverages can damage the liver, even in people who do not have Alpha-1.
    • ZZ patients and patients with any indication of liver damage should avoid alcohol completely.

3. Be aware of your work and home environment.

  • Avoid exposure to dust and fumes.
  • Assess your home and work environments for environmental irritants, such as dust, flower and tree pollen, fumes, and other allergens.

4. Monitor over-the-counter remedies.

  • Carefully review labels of over-the-counter medications, vitamins, or herbal supplements.
  • Avoid products containing acetaminophen or alcohol, both of which can injure the liver.

For more health tips, visit the Alpha-1 Foundation.

Important Safety Information

Alpha1-Proteinase Inhibitor (Human), Zemaira® is indicated to raise the plasma level of alpha1-proteinase inhibitor (A1-PI) in patients with A1-PI deficiency and related emphysema. The effect of this raised level on the frequency of pulmonary exacerbations and the progression of emphysema have not been established in clinical trials.

Zemaira may not be suitable for everyone; for example, people with known hypersensitivity to components used to make Zemaira, those with a history of anaphylaxis or severe systemic response to A1-PI products, and those with certain IgA deficiencies. If you think any of these may apply to you, ask your doctor.

Early signs of hypersensitivity reactions to Zemaira include hives, rash, tightness of the chest, unusual breathing difficulty, wheezing, and feeling faint. Immediately discontinue use and consult with physician if such symptoms occur.

In clinical studies, the following adverse reactions were reported in at least 5% of subjects receiving Zemaira: headache, sinusitis, upper respiratory infection, bronchitis, fatigue, increased cough, fever, injection-site bleeding, nasal symptoms, sore throat, and swelled blood vessels.

Because Zemaira is made from human blood, the risk of transmitting infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent, cannot be completely eliminated.

Please see full prescribing information for Zemaira.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

CSL Behring

Zemaira is manufactured and distributed by CSL Behring LLC.
Zemaira® and CareZ® are registered trademarks of CSL Behring LLC.

© 2018 CSL Behring. The product information presented on this site is intended for US residents only.
ZMR14-04-0006d(1) 5/2015